Wiloch-Szyborska

26 posts

Investigation of copper binding competition between a potential anti-Alzheimer’s drug and Aβ(1–16) based on voltametric and chemometric analysis

Within her SONATINA grant, Magda is conducting research on a new potential therapeutic molecule: TDMQ20. In our previous posts, we described her electrochemical studies, which helped better understand the redox properties of TDMQ20 itself and its complexes with copper ions (Cu(II)). The next stage of the project focused on investigating the extent […]

Boranils as Photocatalysts for Molecular-Oxygen Activation and Perfluoroiodoalkane Reduction

A new study on boranil photocatalysts just dropped! Collaboration is very important for our research group. For this reason, Magda once again supported the team of Prof. Tomasz Kliś from Warsaw University of Technology by carrying out voltammetric studies as part of their research on halogenated boranil complexes. In this […]

Ion-Mediated Adsorption of Amyloid-β Peptides at the Liquid/Liquid Interface: Insights from Electrochemistry and Molecular Dynamics Simulations

As a nice New Year’s gift, our article about Amyloid-β adsorbed at the ITIES was published in ACS Electrochemistry. In this paper, we investigate the behaviour of two different peptides, Aβ(1-16) and Aβ(4-16), at the liquid|liquid interface. There are many publication describing the adsorption of proteins at the ITIES (e.g. […]

Spectroelectrochemical studies of TDMQ20: A potential drug against Alzheimer’s disease – Part 2 – Cu-complexes

The story of spectroelectrochemistry continues… It took a year, but here it is – the second paper by Magda in collaboration with Professor Álvaro Colina’s research group! The sheer amount of data and the depth of analysis required a lot of time and effort, but it was absolutely worth it. […]

Spectroelectrochemical properties of 8-aminoquinoline: voltammetric and computational studies

We are happy that we just published a new paper in a special issue of the Journal of Solid State Electrochemistry dedicated to the 60th birthday of Prof. Frank Marken from the University of Bath. The special issue is edited by Frank’s former supervisor, the legendary Prof. Richard G. Compton, […]

Cu(II) binding to an antimicrobial shrimp peptide – a small step for structural chemistry, a big leap for medicinal applications

Conference trips can bring new collaborations, especially when you are open to discussions and meeting new people (read scientists). At the 2nd French-Polish Chemistry Congress held in 2023, Martin heard Magdalena Rowińska-Żyrek give a talk on the antimicrobial properties of Zn- and Cu-complexes with peptides from shrimp and this meeting […]

Bioinorganic Chemistry Meets Microbiology: Copper(II) and Zinc(II) Complexes Doing the Cha-Cha with the C-t-CCL-28 Peptide, Dancing till the End of Microbes

Peptides is Magda’s favourite topic. So far, she has mainly focused on beta-amyloids. However, in cooperation established with the University of Wroclaw she has had the opportunity to study a new group of peptides. In our new article published with Joanna Wątły’s group this is motivated by “[t]he necessity to […]

Spectroelectrochemical studies of TDMQ20: A potential drug against Alzheimer’s disease

Collaboration is extremely important to us. Gaining new knowledge, both practical and theoretical, is also extremely important. For this reason, Magda went on a 6-month internship to Professor Alvaro Colina’s group in Burgos, Spain. The cooperation turned out to be very successful because shortly after her return our first article […]

Photocatalytic oxidation of benzylamines and sulfides using selected organoboron complexes as molecular oxygen activators

Magda once again cooperated with the Warsaw University of Technology (prof. Tomasz Kliś). As part of this cooperation, a new article entitled was published in Dyes and Pigments. The group from WUT obtained 5 boron-containing dyes. These substances were tested as photosensitizers for singlet oxygen activation. Among the studied compounds, […]